The city council holds around 157 skeletons in its collection together with a number of cremations, held in the museum store in Hilsea.
Most of the human remains date from the Bronze Age (c.2, 500 - 800 BC) and Saxon times (AD c.450 - 1066) and have been excavated during rescue archaeology – for example where they would have been destroyed during the building of a new road.
The two skeletons that will be studied were excavated by the Ministry of Works from Saxon cemeteries at Snell's Corner and Southwick Crossroads during the 1940s and 50s, and from a Portsmouth Museum Service excavation at the Bevis Grave Saxon Cemetery in 1974 - 76.
Two samples of bone will be removed from each skeleton - one of which had TB of the spine and the other was disease free. The disease-free sample will be used as the control.
Professor Charlotte Roberts from Durham University and Professor Terry Brown from Manchester University are leading the research, which is being funded by the Natural Environmental Research Council.
Portsmouth Museum are keen to stress that the remains will be treated respectfully throughout the process to comply with DCMS guidelines and standards.
"The Museum and Records Service feels privileged to be involved in this important work,” added Jennifer, “which will contribute to cutting edge scientific research and potentially the development of new drugs to combat TB."