Visitors will be able to walk around the museum, which is part of Manchester University, with a museum curator, anti-slavery campaigner Thomas Clarkson, African and British slave traders, escaped slave James Watkins and a Lancashire cotton worker.
The play, This Accursed Thing, was developed by Tony Jackson, a senior lecturer in drama at the university, and written by one of the actors, Andrew Ashmore, based on research into the slave trade and its connections to the museum’s collections.
It explores the hidden – and often contentious – stories behind the collection.
“At first glance you might wonder why a performance about slavery is taking place alongside the famous archaeological, botanical and Egyptology exhibits – amongst others,” said Tony Jackson.
“One answer is that parts of the collection were paid for by wealthy individuals who benefited from the slave trade.”
“This is a history behind a history: it’s a chance for Manchester to acknowledge its slave trade links – but also to remember the proud contribution the city made to its abolition.”