"This will be a fantastic resource for social science, history, arts and humanities Higher Education students and researchers, but also family historians and the general public," said Patrick Fleming, head of the British Library Reader and Reference Services.
"Newspapers are the first draft of history and much of this material isn't only invaluable in research terms but provides also unique means of getting as close to contemporary life and culture as you possibly can."
The ncse closely reflects the print culture of the 1800s, which was characterised by serials and interconnected publications. Individual issues and editions as a whole are searchable on the site, both of which can be browsed by digitally turning the pages of the periodicals.
The website will be online at www.ncse.ac.uk from May 13.
The ncse has been funded by the Arts and Humanities Research Council.